Go into your Smite install folder and navigate to the REDIST folder.
Standalone Launcher: ...\Program Files (x86)\Hi Rez Studios\HiRezGames\Smite\Binaries\Redist
Steam: ...\Program Files (x86)\Steam\steamapps\common\SMITE\Binaries\Redist
Run 'UE3Redist_vs2012.exe' from this folder.
If this does not work, follow the instructions below to uninstall and reinstall your Microsoft Visual C software.
1. In Windows, go to: Control Panel > Uninstall a Program
2. Right click and uninstall the following items:
- Microsoft Visual C 2012 (x64)
- Microsoft Visual C 2012 (x86)
- Microsoft Visual C 2010 x86 Redistributable
3. Now re download and install the following:
C 2012 x64/x32
http://www.microsoft.com/en-us/download/details.aspx?id=30679 (select "x86" AND "x64" - be sure you install both)
C 2010 x32
C 2010 SP1 x32
4. Reboot your PC when this is done and try launching the game.